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Q3 2026 earnings ā€¢ released ā€¢ EPS miss -11.37%
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SYRE:NASDAQ
Spyre Therapeutics Inc
$103.86
+7.53%
(+7.27) 1D
$103.00
-0.83% (-0.86)
After hours
Closed: Nov 6, 4:00:00ā€ÆPM GMT-5  ·   USD
All symbols
SymbolPriceChange% Change
Generating top insights for SYRE...
Open
$98.35
High
$104.30
Low
$97.29
Mkt. cap
9.86B
Avg. vol.
1.28M
Volume
1.64M
52-wk high
$110.18
52-wk low
$21.14
EPS
-$3.22
Beta
3.24
Shares outstanding
94.97M
No. of employees
130
Open
$98.35
High
$104.30
Low
$97.29
Mkt. cap
9.86B
Avg. vol.
1.28M
Volume
1.64M
52-wk high
$110.18
52-wk low
$21.14
EPS
-$3.22
Beta
3.24
Shares outstanding
94.97M
No. of employees
130
News stories
From web sources and news partners
About Spyre Therapeutics Inc
CEO-
Employees130
FoundedJan 1, 2013
HeadquartersWaltham, Massachusetts, United States
SectorHealth Care
IndustryBiotechnology
Websitespyre.com
Analyst ratings
Based on 13 analysts giving stock ratings to SYRE in the past 3 months
Strong buy
Buy
13
Hold
0
Sell
0
12-month forecast
Based on 13 Wall Street analysts offering 12 month price targets for SYRE in the last 3 months.
Highest
Current $103.86
$135.00 (+29.98%)
Average
$122.92 (+18.35%)
Lowest
$110.00 (+5.91%)
Analyst
Recommendation
Action
Price target
Projected
Date
Yanan Zhu
Wells Fargo
Buy
Reiterated
$115.00
+10.7%
11/05/2026
Debanjana Chatterjee
JonesTrading
Buy
Maintained
$130.00
+25.2%
11/04/2026
Yatin Suneja
Guggenheim
Buy
Reiterated
$135.00
+30%
11/03/2026
Julian Harrison
BTIG
Buy
Maintained
$121.00
+16.5%
11/04/2026
David Nierengarten
Wedbush
Buy
Maintained
$120.00
+15.5%
11/04/2026
Alex Thompson CFA
Stifel Nicolaus
Buy
Reiterated
$131.00
+26.1%
11/04/2026
Samantha Semenkow
Citi
Buy
Maintained
$119.00
+14.6%
10/21/2026
Unknown Analyst
UBS
Buy
Initiated
$120.00
+15.5%
10/11/2026
Alice Nettleton
UBS
Buy
Initiated
$120.00
+15.5%
10/11/2026
Priyanka Grover
J.P. Morgan
Buy
Initiated
$110.00
+5.9%
10/01/2026
Hardik Parikh
J.P. Morgan
Buy
Initiated
$110.00
+5.9%
10/01/2026
Akash Tewari
Jefferies
Buy
Maintained
$126.00
+21.3%
09/09/2026
Thomas Smith
Leerink Partners
Buy
Reiterated
$128.00
+23.2%
09/10/2026
Sam Slutsky
LifeSci Capital
Buy
Maintained
$116.00
+11.7%
09/08/2026
David Hoang
Deutsche Bank
Buy
Maintained
$127.00
+22.3%
08/26/2026
Colleen M. Kusy
Robert W. Baird
Buy
Maintained
$120.00
+15.5%
08/05/2026
Andy Chen
Wolfe Research
Hold
Downgraded
-
-
07/28/2026
Joseph Catanzaro
Mizuho Securities
Buy
Maintained
$120.00
+15.5%
07/13/2026
Tyler Van Buren
TD Cowen
Buy
Maintained
-
-
06/23/2026
Umer Raffat
Evercore ISI
Buy
Maintained
-
-
06/03/2026
Unknown Analyst
Guggenheim
Buy
Reiterated
$115.00
+10.7%
05/06/2026
Martin Auster
Raymond James
Buy
Initiated
$80.00
-23%
04/10/2026
Last report
Nov 3, 2026
Fiscal period
Q3 2026
-$0.94 / -$0.84
-11.37%miss
Revenue / Est. (USD)
- / 0.00
Fiscal Q3 2026 earnings call
Waiting for the earnings call
At a glance
Insights from the latest news and reports
Previous reportsAll values in USD
Loading Previous Earnings...
Revenue
Net income
All values in USD
Dec 2025
Mar 2026
Jun 2026
Sep 2026
Revenue
-
-
-
-
Cost of goods sold
44.64M
60.41M
65.50M
89.17M
Cost of revenue
44.64M
60.41M
65.50M
89.17M
Research and development expenses
-
-
-
-
Total research and development expenses
-
-
-
-
Selling, general, and admin expenses
12.53M
15.23M
16.14M
16.55M
Operating expense
12.53M
15.23M
16.14M
16.55M
Total operating expenses
57.17M
75.64M
81.64M
105.72M
Operating income
-57.17M
-75.64M
-81.64M
-105.72M
Other non operating income
-12.50M
-30.36M
-4.61M
-1.03M
EBT including unusual items
-62.53M
-69.00M
-36.20M
-96.12M
EBT excluding unusual items
-62.53M
-99.00M
-76.20M
-96.12M
Income tax expense
-
-
-
-
Effective tax rate
-
-
-
-
Other operating expenses
-
-
-
-
Net income
-62.53M
-69.00M
-36.20M
-96.12M
Net profit margin
-
-
-
-
Earnings per share
-0.74
-0.74
-0.36
-0.94
Interest and investment income
7.14M
7.00M
10.05M
10.62M
Interest expense
-
-
-
-
Net interest expenses
7.14M
7.00M
10.05M
10.62M
Depreciation and amortization charges
-
-
-
-
EBITDA
-
-
-
-
Gain or loss from assets sale
-
-30.00M
-40.00M
-
Insider transactions
Insider transactions data is drawn from third-party sources. Learn more
Insider
Position
Type
Date
Shares
Amount
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